Pharma News and Events
News, reports and events on transport, storage, distribution and logistics for temperature-sensitive pharmaceutical and healthcare products
What’s on in pharma…
Cool Supply System & Solutions 2017
Date: 23-24 March 2017
Venue: Parker Hotel Brussels Airport, Belgium
4th Middle East Pharma Cold Chain Congress
Date: 10-12 April 2017
Venue: Dubai, UAE
Pharmaceutical Logistics Conference
Date: 18-19 May
Venue: Copthorne Tara Hotel, London, UK
Contact: SMi Group
Date: 25-27 April 2017
Venue: Montreux Music & Convention Centre, Switzerland
Pharmaceutical Logistics conference for London
The 11th annual Pharmaceutical Logistics Conference takes place in London on 18 and 19 May. The conference will include papers on strategies to maintain supply chain security, visibility and anti-counterfeiting with presentations from Exelcius, Seer Pharma, Johnson and Johnson, Merck, Sharpe and Dohme, GlaxoSmithKline, Eli Lilly, Sanofi, IATA, AstraZeneca, ASC Associates, TEDAC, and Turkish Cargo.
The full roster of the speakers as well as their presentations can be viewed at www.pharmaceutical-logistics.com/GCCpr. The two-day event will also provide in-depth discussions on the demands of temperature regulation, warehousing and supply chain efficacy, innovation within clinical trial logistics, and regulatory considerations within the pharmaceutical industry.
The worldwide threat of counterfeiting and supply chain security continues to escalate with reports of fake drugs still slipping into public health systems despite rigorous regulatory schemes. Key presentations to include:
- AN APPROACH TO GLOBAL SUPPLY CHAIN SECURITY
Tom Cochrane, head of security operations, Mundipharma
Case studies on how to manage security systems to mitigate risks of damage, temperature excursion, bribery and corruption, as well as using networks and technology for a multi-layered approach. The presentation will also include looking at investigations such as paper trails, CCTV footage and forensic analysis to identify causes of incidents.
- GS1 STANDARD – A CRITICAL TOOL IN THE FIGHT AGAINST COUNTERFEITING
Glen Hodson, head of healthcare, GS1
Explores GS1 standards as a tool to prevent counterfeiting and knowing regulatory bodies taking action. This will also discuss authentication and traceability.
- THE IMPACT OF THE FALSIFIED MEDICINES DIRECTIVE TO THE SUPPLY CHAIN
Martin FitzGerald, deputy director general, European Healthcare Distribution Association (GIRP)
This presentation will expound on the Falsified Medicines Directive& Delegated REgulation, the development of European Medicines Verification Systems as well as the cost implications for operators and latest developments.
- HOW TAPA MITIGATES SUPPLY CHAIN SECURITY RISKS
Jason Breakwell, vice chairman, Transported Asset Protection Association
A discussion on intelligence analysis, mitigation measures for facilities and transportation as well as identification and evaluation of supply chain risks.
WCA Pharma to set new standard
Miami, Florid, US: WCA Pharma plans a new global standard for shipping pharmaceutical and life science products.
“Our goal is to set the new international standard for the movement and logistics of pharmaceutical and life science products,” said Adam Mckenna, manager of WCA’s Perishables, Time Critical and Pharma networks.
“By doing so, we’ll be able to ensure that our member’s services far surpass current industry standards for quality and compliance.”
WCA Pharma is a logistics group of WCA World, a network of pharmaceutical forwarders
“We are aiming higher than the EU, GDP, CEIV and PIC/s (Annex 15),” said Adam Mckenna. “WCA members who are certified will truly be the best of the best in pharmaceutical and life sciences logistics and handling. In time, we are confident that this validation process will become the international standard in the sector.”
Alan White to lead the supply chain special interest group
Derby, UK: Alan White, managing director, Fresh Pharma, will be working in partnership with Medilink East Midlands, the life science industry association whose aim is to help companies establish, develop and grow.
Alan is the new leader of Medilink EM’s special interest group. The group’s aim is to create an environment where academics, clinicians and businesses can meet, learn from each other and explore possible collaborations that will ultimately lead to commercialisation of innovative products and services within the healthcare remit.
‘It’s really exciting to be offered the opportunity to lead and develop the Supply Chain Special Interest Group, and I look forward to creating many synergies and enhancing capabilities across the East Midlands,” White says.
“Fresh Pharma have been members of Medilink EM for two years now, and were proud to be selected as finalists in the Medilink East Midlands ‘Collaboration with the NHS’ category of the Business Awards for 2016.”
The supply chain special interest group events are free to attend thanks to support from the European Regional Development Fund and are delivered by Medilink East Midlands as part of the Instil programme, a project part-funded by the European Regional Development Fund.
India: Agility opens pharma storage centre in Hyderabad
Hyderabad, India: Freight forwarder Agility has opened its first temperature-controlled life sciences storage and handling site in Hyderabad in partnership with cold chain container company va-Q-tec.
The 557 sq metre site, based at Rajiv Gandhi International Airport, aims to serve pharma manufacturers in the city along with Goa, Pune, Visakhapatnam and Bengaluru.
Detlev Janik, chief executive of Agility South Asia, said: “This new centre will help the fast-growing Indian life sciences companies to meet the rising global demand for their products.”
Dr Joachim Kuhn, chief executive of va-Q- tec, said: “Our partnership with Agility is a further example of how va-Q- tec develops and provides transportation systems with accompanying services for life sciences logistics. The cooperation will further strengthen va-Q- tec’s footprint in India, one of the fastest growing pharma exporters.”
Qatar Airways Cargo adds new pharma flights
Doha, Qatar: Qatar Airways Cargo has launched new Pharma Express flights from the pharmaceutical hubs of Basel (EuropAirport) and Brussels Airport to Doha.
Qatar added an additional weekly frequency, operating on Fridays, from Basel to Doha on 3 February while two new Airbus A330 freighter services from Brussels to Doha on Wednesdays and Saturdays will begin on 15 February.
Basel and Brussels are both home to the headquarters of major pharma companies.
Qatar Airways’ chief officer cargo, Ulrich Ogiermann says: “At Qatar Airways Cargo, we understand the intricacies involved in safeguarding the integrity of temperature-sensitive commodities during shipment. Therefore, we are committed to offering our customers seamless cool chain air logistics as well as uncompromised service standards compliant with Good Distribution Practice (GDP) requirements.
“Our Pharma Express flights are launched to cater to the rapidly expanding pharmaceutical industry. We are extremely proud to be the only international air cargo carrier to offer dedicated Pharma Express flights to the world’s major pharmaceutical and healthcare industry hubs.”
Pharma Express flights were launched in 2015 and currently operate from pharma hubs of Brussels, Basel, Mumbai, Ahmedabad and Hyderabad, transporting more than 30,000 tonnes of pharma products a year.
Bulk shipper available for sale or rent
London, UK: Peli BioThermal’s new pallet shipper system, the Crēdo TM Cargo, is available to buy and rent.
The passive temperature-controlled bulk shipper has high performance and robust reliability for the global transport of pharmaceutical payloads, the company says.
Following an intensive design, testing and qualification process the pallet accepting bulk shipper is in full production launching in the marketplace in January 2017.
The production version was unveiled at the 16th Annual Temperature Controlled Logistics, Europe event, held at London’s ExCel exhibition centre. The reusable system, designed specifically to accept a full ISO pallet, is helping to revolutionise the temperature-controlled bulk shipper market.
David Williams, president, Peli BioThermal, said: “The Crēdo Cargo is a pallet accepting shipper, so it’s load and go of the payload from a client’s temperature controlled warehouse into the protection of the Crēdo Cargo and safe transit on to the final destination.”
The pioneering product is the result of intensive and extensive research and development collectively carried out by Peli BioThermal’s New Product Development team. The in-depth, pioneering process has been documented via a diary of innovation video available soon on the Peli BioThermal website.
The Crēdo Cargo is a robust, reliable, high performance pallet accepting system provides a tough external wall construction designed to absorb and deflect impacts and is purposefully designed for four way pallet jack and forklift handling. Greg Wheatley, vice president, worldwide product development and engineering, Peli BioThermal said the product is “a real game changer in the industry”.
“Our industry renowned qualification and testing process is second to none so customers can have the confidence in this product that possesses an easy to use coolant loading system and is flat-pack, modular and stackable.” The new bulk shipper, uses PCM coolants coupled with the unique slot-in components, ensures high performance and consistent temperature stability in excess of 120 hours. Its robust design makes it ideal for the rigours of global logistics applications.
Kuehne+Nagel receives IATA CEIV Pharma certification for entire network
Schindellegi, Switzerland: Kuehne+Nagel has gained IATA CEIV Pharma network certification of its entire world air network.
The International Air Transport Association (IATA) introduced the CEIV Pharma Standard in 2015. CEIV Pharma aims to improve competency in the air logistics industry as a response to increasing regulatory requirements and the demands of the world’s largest pharmaceutical companies.
Independent certification of the current and any future expansion of the KN PharmaChain network under the IATA CEIV Pharma programme is in line with the Kuehne+Nagel strategy of using audits by external parties to maintain its own GxP standard at the highest levels.
CEIV Pharma network certification confirms the quality and risk based credentials of the award winning KN PharmaChain. A unique web-based risk assessment tool is now used to complete a risk assessment at a lane level and all Standard Operating Procedures (SOPs) are managed via a pharma compliant document management system. During the trans- portation process, KN PharmaChain can additionally provide real-time monitoring and visibility through the use of active transmitting sensors and proactive intervention via the 24/7/365 CareTeam. All of this is supported by highly trained personnel and dedicated facilities. Compliance to the required WHO TRS957 standard was validated through rigorous audits at global locations around the entire KN PharmaChain network.
Bolloré Logistics France receives Pharma certification from IATA
Paris, France: Bolloré Logistics becomes the first transport and logistics company in France to receive the IATA CEIV Pharma certification for its Paris Roissy site after having received it for its sites in Brussels (Belgium), Frankfurt (Germany) and Lisbon (Portugal).
The aim of Bolloré Logistics is to deploy this action throughout its global network.
“By certifying our hubs around the world we are able to guarantee our customers air freight transportation respecting the cold chain and the strict quality standards required by the pharmaceutical industry. This certification demonstrates our ability to standardize our end-to-end processes from origin to final destination,” said Brice Bellin, healthcare director Europe, Bolloré Logistics.
“Cold chain management, especially with healthcare products, must meet the requirements of quality and reliability. Shippers expect standardisation and transparency throughout the supply chain and want to be assured that facilities are equipped and operated throughout the highest standards.
The CEIV Pharma certification meets all these requirements and more. Bolloré Logistics took up this CEIV Pharma certification challenge. Their success will result in a stronger and more competitive airfreight service for this vital sector of the global economy,” said Nick Careen, senior vice president, Airport, Passenger, Cargo and Security of IATA.
Temperature controlled logistics strategies for the future
London, UK: The future of the pharma cold chain logistics industry is in good shape, with sturdy growth being forecasted for the $12billion market, says a new report.
Pharma Logistics IQ’s Temperature Controlled Logistics Future Trend Report examines the oncoming strategies likely to blossom in the cold chain industry.
In late 2016, Pharma Logistics IQ conducted an online survey to assess current perceptions on how the cold chain industry is likely to evolve over the next few years.
The survey gathered the responses of the many stakeholders in the international cold chain community with input from the likes of: Eli Lilly and Company, Korea Astellas Pharma, Ministry of Health – Morocco, Ghana Health Service, NovartisMarkets and Genentech.
Many experts are of the opinion that a range of trends are due to take hold in the industry. The rise of cell and gene therapies and the logistics paths they require (patient to manufacturer to patient, for instance) and the inherent sensitivity of the biomaterials will place new demands on the industry.
The report notes that we are due to see packaging and network designs become more tailored for specific drugs. “We are seeing a trend in pharmaceutical manufacturers beginning to design their cold chain networks specifically to the drug platform or modality based on therapeutical area. The ability to tackle a whole range of chronic diseases and illnesses with exciting new technologies has driven more and more specialization in not only the cold chain but the entire logistics network,” Phamra IQ says.
“For example, stable and better characterized drugs with an exemplary safety record are using deferred shipping lanes, new transport modes including ocean freight, and an increased allowable range in shipping temperatures. However, more fragile platforms like a monoclonal antibodies require greater characterization of the drug product not only for temperature hazards, but a full range of environmental hazards including shock, vibration, temperature and humidity.
“The characterization of these synthesized human proteins in solution has shown a fragility that requires complex and specialized logistics networks supported by cushioning thermal packaging with tight control on temperature ranges. Coupled with the controlled temperature requirements for small molecule drugs, the depth and complexity of modern pharmaceutical supply chains will grow exponentially.
“There are also new strategies appearing in terms of packaging conduct, payload volumetric efficiencies in packaging to leverage innovative techniques and metric calculations to maximise container utilisation. Also, some have been experimenting with the use of multi-cell trailers—refrigerated trailers with insulated curtains hung at intervals to create different temperature zones.
“Some peer pharma firms in the industry have noted the value in cross-firm collaboration on shipments and lanes to improve efficiency instead of having vacant space shipped due to packaging size constraints. The global insulated packaging marked is due to mature at a rate of 5.68% CAGR to 2020, driven by demand from the pharma industry.
“Experts are contemplating the impact that will be incurred on the cold chain by 3D Printed pharmaceuticals and the use of drones for delivery.”
Peli BioThermal new passive bulk packaging
Plymouth, MN, US: Peli BioThermal has launched CoolPall Vertos Advance, a passive shipper that can be placed in refrigerated storage, when necessary, during transport.
It builds on the success of the existing CoolPall Vertos pioneering packaging product range, the company says.
The new CoolPall Vertos Advance extends and further enhances Peli BioThermal’s current range of single-use bulk shippers. Customers can now choose CoolPall Vertos Advance, which utilises PCM and integrated VIPs, while the original CoolPall Vertos range incorporates water-based coolants.
“With a volume of 1680 litres, the newly unveiled CoolPall Vertos Advance ISOPAD has a temperature range of 2 – 8C and duration of up to five days. This latest launch further extends the family of CoolPall Vertos products, which are already available in four sizes and two temperature ranges.”
“CoolPall Vertos Advance’s reliable, robust specifications make it ideal for the rigours of global logistics applications covering routes to more exotic locations such as Brazil, Russia, the Far East including Indonesia and Eastern European destinations, where there is an increasing need to be able to put a shipment in refrigerated storage for part of its journey.”
World Courier has lighter thermal packaging
London, UK: World Courier has new packaging for pallet-sized shipments that will reduce transport costs and maintain temperature up to 40 percent longer than comparable products.
The passive pallet shipper, called Cocoon, marks the first packaging innovation from World Courier’s Climate Optimisation Research & Engineering (CORE) Labs – a science-led and data-driven solutions center launched in 2015 to help pharmaceutical manufacturers make the most informed packaging decisions.
“With Cocoon, we’re able to address a need that was introduced to us by our customers and provide shippers with a cost-effective, temperature-controlled packaging solution for large-scale, high-value shipments being transported long distances”
Composed of honeycomb vacuum-insulated panels, Cocoon weighs 15-to-30% less than comparable packaging products, covers Euro and US pallet sizes, and supports three temperature range requirements: -15 to -25 degrees Celsius, 2-8 degrees Celsius and +15 to +25 degrees Celsius.
The vacuum-insulated panels, coupled with Cocoon’s phase change materials provide a high-level of thermal protection and stability for temperature-sensitive pharmaceutical products throughout long-distance deliveries.
Airside pharma transport at Brussels Airport
Paris, France: Brussels Airport showed off a European first at the TIACA Air Cargo Forum in Paris: the active version of the Airside Pharma Transporter.
This trailer is at the temperature to hold pharmaceutical shipments within the correct temperature limits during transport between warehouses and aircraft. The period on the tarmac is considered the most hazardous link in the transport process.
The active version of the Airside Pharma Transporter ensures that the inside temperature is at the correct temperature eliminating the need for the handling agents to condition the transport vehicle and results in quicker cycle times between different transports.
The Airside Pharma Transporter relies on solar power to operate autonomously for several days.This allows for energy neutral temperature-controlled transport of the temperature-sensitive pharmaceutical shipments at Brussels Airport.
Steven Polmans, head of cargo, Brussels Airport says: “Brussels Airport commits to an ongoing dialogue with the shippers of pharmaceutical products in order to know their needs and specific expectations for air transport”
“The Airside Transport Pharma Project is an excellent example of an innovation aimed at solving a priority issue indicated by the shippers. Pharmaceutical manufacturers were actively involved in defining the performance requirements for the engineering and the test protocol for the temperature mapping of the airside transport solution.”
Alban François, vice president global cargo, Brussels Airlines Cargo, says: “With the Airside Pharma Transporter, Brussels Airlines Cargo will be able to guarantee 100% temperature control of all pharma shipments during the ramp transportation at BRU, and this independently of the outside temperature. Having this solution on our hub is a major achievement for our customers.”
Sonoco ThermoSafe’s innovative new cold chain technology
Sonoco ThermoSafe’s Certis Platform of Universal Parcel Shippers have been awarded First Place as “Most Innovative New Cold Chain Technology” at the IQPC Cold Chain Global Forum.
The LD7 Quarter PMC Pallet Shipper was honored as a Runner-Up.
The Most Innovative New Cold Chain Technology of the Year award is software that is breaking new ground in the temperature-controlled arena; offering new levels of supply chain visibility, improved product quality and compliance, and/or reduced costs and temperature excursions, the company says.
The Certis Platform of Universal Parcel Shippers suit one-way shipments of temperature-sensitive products and use the same universal pack-out configuration regardless of season for refrigerated, CRT and frozen solutions for both 72 hour and 120 hour durations.
The LD7 Quarter PMC Pallet Shipper delivers industry leading performance, driven by innovative new technology, and offers design simplicity. The patent pending design features unique “L” shaped insulation panels that eliminate corner leaks and drastically reduce edge leaks through interlocking design. In addition, ConvecTech dispersion panels promote natural convection and enable simple pack-out procedures. These innovative new technologies have improved the thermal performance capabilities of a passive pallet shipper while drastically simplifying the pack-out procedures. Furthermore, the LD7 Quarter PMC passive pallet shipper optimized the footprint within a wide-body aircraft further reducing costs.
Drug transport – new smart boxes track drug temperatures during transit
Poznan, Poland: Wrocław’s Independent Clinical Public Hospital in Poland has chosen Blulog’s innovative boxes with integrated temperature traceability and temperature monitoring solutions with integrated alert systems for the transport of drugs.
The NFC data loggers are integrated in isothermal boxes to ensure the proper drug temperature maintenance during transport to laboratories, hospitals or pharmacies. Blulog says that the NFC temperature loggers are credit-card sized, autonomous and very affordable. Storage conditions are crucial to successfully transporting drugs or biological material, where even minor temperature variations can cause substances to deteriorate. The units contain NFC data loggers to monitor cytotoxic drugs, which are effective at 2–8°C.
The hospital in Poland can access the data in three ways: using an NFC reader or NFC-enabled smartphone, via the Bluconsole web application, or via email, where all information is securely stored. The Independent Clinical Hospital currently owns 20 NFC-labelled boxes.
When the package arrives, it is verified once again by the medical staff. A coloured diode on the data logger indicates any temperature excursions: red indicates that the transport’s parameters should be verified. The system is thoroughly secure and encrypted, ensuring no potential data manipulation.
“Cytotoxic drugs are highly susceptible to atmospheric conditions and require specific packaging,” says Jérémy Laurens, sales and marketing director for Blulog. “During the whole transportation process, the drug should be kept within the temperature range of 2–8°C, outside of which the substance becomes ineffective.”
Blulog is a French-Polish firm based in Poznan that provides data loggers for standard isothermal boxes made by Georg UTZ.
Onset launches two new products for pharma cold chain monitoring
Boston, Massachusetts, US: Onset is expanding its InTemp range of pharmaceutical cold chain management products with the launch of new temperature loggers and a cloud-based data warehousing service.
Together with Onset’s CX400 Series loggers and InTemp mobile application, the products provide end-to-end visibility throughout the pharmaceutical supply chain—from the manufacturing plant, across distribution, to pharmacies, clinics and other healthcare facilities.
Bluetooth enabled InTemp CX500 Series loggers provide in-transit temperature monitoring—without the need to open boxes—to reduce temperature excursions and handling errors. Onset says the loggers offer a ‘cost-effective alternative to global positioning system-based solutions’ and automatically transmit mission-critical temperature data to smartphones and tablets – without the need to risk compromising the environment by opening boxes or refrigeration units to access data.
Meanwhile, the InTempConnect cloud-based data warehousing service enables command-centre control over all logger deployments throughout the global supply chain. And like all InTemp products, the new solutions achieve 21 CFR Part 11 compliance, ensuring electronic records and electronic signatures are trustworthy and reliable.
“Today’s temperature monitoring solutions have not kept pace with growing government and market pressures for pharmaceutical companies to validate the integrity of their products and gain tighter control over costs,” said Paul Della Villa, product marketing manager for Onset. “Our expanded line of InTemp pharmaceutical cold chain monitoring solutions addresses that innovation gap by harnessing mobile and cloud technology to bring unprecedented ease of use, cost effectiveness, and comprehensive functionality to monitoring the entire distribution chain.”
Parexel tracking and monitoring
Boston, Massachusetts, US: Parexel has launched its Active Tracking service. The service follows good distribution practice requirements by providing biopharmaceutical companies with near real-time temperature and location monitoring of investigational medicinal products from central distribution centers to clinical trial sites.
Parexel’s Active Tracking service uses supply chain monitoring technology to detect incidents, such as shipment delays, shipment diversions, and temperature deviations. When combined with Parexel ClinPhone, temperature and location data is automatically sent in near real-time to clinical trial sites for assessment.
This integration enables greater automated preventive or remedial actions, such as release, quarantine, and automatic re-order of temperature-controlled products, simplifying temperature management for sites and sponsors.
“In the past, an investigational site had to wait until it received a shipment and downloaded the data from the temperature logger to find out if a drug’s temperature had been compromised,” said Sanjay Vyas, corporate vice president, Clinical Trial Supplies & Logistics, Parexel.
IAG to build Heathrow handling site
Heathrow, UK: IAG Cargo is to build a freight handling site facility at its London Heathrow Hub.
The new building will be twice the size of IAG Cargo’s existing Premia site. It will have a larger dedicated Constant Climate Quality Centre for pharmaceuticals.
The site will operate alongside IAG Cargo’s existing Premia site and handle all express Prioritise shipments and passive Constant Climate shipments.
Drew Crawley, chief executive, IAG Cargo said: “IAG Cargo’s four airlines now carry more premium freight than at any point in their combined history. With the continued growth of high speed e-commerce and cool chain logistics in particular , as well as the ongoing expansion of the IAG family and network, we need facilities that are ready for the next generation of premium freight.”
“We believe that the blend of our next generation aircraft, new freight facilities such as this one and our expanding network means that IAG Cargo is extremely well positioned in the market to meet the current and future premium freight demands of all our customers. Our new premium warehouse will be built away from existing Premia, leaving our current operation and customer service unaffected”.
Cold Chain Technologies Wins Most Innovative New Cold Chain Technology of the Year
Holliston, Mass, US; Cold Chain Technologies received the 2016 Cold Chain Global Excellence Award for “Most Innovative New Cold Chain Technology of the Year” for its Koolit Advanced PCM Gel refrigerant.
Held on 29 September in Boston MA, the Cold Chain Global Forum Excellence Awards honour, recognise and promote the most innovative supply chain practices, solutions and individuals over the past year.
Koolit Advanced PCM Gel is the first commercially available solid phase change material refrigerant engineered to maintain the efficacy of drugs and vaccines during transport. This new gelled technology allows package designs that reduce size, improve thermal efficiency and performance and are leak-proof.
Cold Chain Technologies will introduce these new materials to its product lines this year.
Thermal shipping systems using Koolit Advanced PCM Gel are lighter and smaller than traditional water-based shippers and are less costly and ensure better coverage than PCM bottles and can be applied in either single-use or return/reuse applications, the company says.
“We continually seek and identify opportunities that will advance the state of our industry and provide our customers with significantly improved solutions. We believe the Koolit Advanced PCM Gel is one of those major advancements. By combining focused engineering and product development with new state-of-the-art manufacturing, we’re able to offer the market a breakthrough solution with the same lowest total cost expectations,” says Larry Gordon, chief executive, Cold Chain Technologies.
Cryoport Wins 2016 Cold Chain Global Forum Excellence Award
The Awards program is the largest and most recognized annual industry event, honoring and celebrating the innovators and thought leading professionals and organizations which have substantially exceeded industry standards. The awards are to highlight the very best of these projects, and give international, industry-wide recognition to those who have earned them.
The award was accepted on September 29th, on behalf of Cryoport, by Robert Moore, in the category of “Most Effective Risk Assessment, Evaluation and Mitigation for Transportation” for the Company’s work with a global animal health company which produces quality vaccines, parasiticides, anti-infectives, medicinal feed additives and other pharmaceuticals, along with diagnostic products and genetic tests.
The winning project was Cryoport’s selection and successful implementation of a complete, outsourced, turnkey management solution for a client’s fleet of cryogenic shipping and storage requirements for animal vaccines, which resulted in the client realizing an approximate $1.6 million reduction in annual costs.
“We are pleased to receive this award. It is a further validation of Cryoport’s ability to deliver unmatched cold chain logistics solutions for the life sciences,” said Jerrell Shelton, chief executive, Cryoport. “Cryoport is the only temperature controlled provider to the life sciences capable of delivering comprehensive outsourced solutions for cold chain logistics fleet management and vital information needs.”
Pharma Cold Chain: regulatory expectations, GDP implementation, distribution planning
London, UK: Over the last 24 months, the industry has witnessed market growth and new logistics hubs established around the globe by forwarders and distributors, to service and support a more round-the-clock global network for pharmaceutical product supply.
But challenges remain with the increasingly fragile biologics product and tightened GDP regulations. Discussing these, the 11th annual Cold Chain Distribution, taking place in London, UK, on 12 and 13 of December, brings together more than a 100 representatives from big pharma, biotech and service providers with responsibilities in supply chain, cold chain, logistics, distribution, packaging, operations, production, manufacturing, QA and QC from all over the world.
“The aviation industry has made improvements for cold chain distribution, despite improvements there are still challenges that remain unanswered. It’s time to discuss the next trends of cold chain distribution as air cargo,” says Frederik Wildtgrube, head of global sales, Finnair.
Cold Chain Distribution 2016 speaker line up includes key decision makers and leading pharma cold chain experts representing MHRA, Danish Medicines Agency, IATA, NHS Blood & Transplant, Sanofi-Aventis, Johnson & Johnson, GlaxoSmithKline, GSK Biologicals, Teva Pharmaceutical, the Grimsby Institute, World Courier, Finnair Cargo, PCI Pharma Services, Cell and Gene Therapy Catapult, Modalis, Exelsius, Vertex International Ltd and more.
The complete 2-day event programme including all speakers and their topics can be viewed at www.coldchain-distribution.com/AJOT.
“We consider SMi’s Cold Chain Distribution conference as the industry-leading event in the UK which has always attracted a good mix and level of speakers and delegates, including both our customers and suppliers, who are all key opinion leaders in their respective fields. It serves as a good platform for us to engage with attendees, share best practices and challenge our theories on the future of temperature controlled distribution. As cold chain distribution is our core business, it’s imperative that we continue to evolve in accordance with the needs of our customers,” says David Spillett, key account director, World Courier.
Latest registered attendees include: MHRA, Genzyme, GlaxoSmithKline, Norgine, GSK, Pfizer, MedImmune, Shire, Janssen Pharmaceuticals, Roche Pharmaceuticals, GW Pharmaceuticals, Janssen Pharmaceuticals, Bristol-Myers Squibb, Porton Biopharma, Copenhagen Capacity, Kyowa Kirin International plc, Day Lewis Plc, Envirotainer, JB360solutions, Wockhardt UK, Biotrans and many more.
Cold Chain Distribution 2016 offers to its attendees a fantastic networking opportunity with the leading experts in the industry at a drinks reception on day one followed by a Gala Dinner (invitation only) hosted by World Courier.
Cold Chain Distribution 2016 is sponsored by: World Courier (Lead Sponsor), Berlinger, Eberspächer, Elpro, Emball’iso, Finnair Cargo, Peli BioThermal, Sensitech, SMO Group, Topa Packaging, Yourway Transport.
Cardinal Health takes Reusable Packaging award
Tampa, Florida, US: Cardinal Health has won the Reusable Packaging Association’s 2016 Excellence in Reusable Packaging award.
Tim Debus, president of the association said: Cardinal Health’s holistic approach and the significant business and environmental results they achieved made their submission stand out.”
“Our judges cited the impressive impact demonstrated in multiple areas, including material safety, material reuse, ergonomics, fuel/emissions, and cost savings as key factors in their selection.”
Cardinal Health delivers refrigerated pharmaceuticals to pharmacies partnering with Sonoco ThermoSafe. Reusable plastic totes with replaceable molded expanded polystyrene liners were already the Cardinal Health standard.
The water-based coolant gel-packs within the totes however were replaced with plant-based PureTemp phase change materials to improve temperature control.
Additionally, a reusable bulk pallet shipper that allows refrigerated and controlled room temperature product to ship on the same truck was developed. This allows Cardinal to avoid the expense of multiple vehicle shipments or moveable bulkheads to create separate temperature environments.
Product spoilage was reduced by 90%, the phase change coolant packs are used an average of 87 times each, and the bulk shippers are used an average of 192 times and counting. Today, Cardinal Health ships $18bn in refrigerated pharmaceuticals in 6.5 million reusable totes per year, while saving $5.6m and avoiding $9.3m in additional cost.
“We have worked very hard across our network to reduce packaging waste through the use of sustainable, reusable packing components that protect costly refrigerated pharmaceuticals,” said Chris Anderson, director of quality systems, Cardinal Health.
“High quality, qualified, durable, reusable, and sustainable packaging is a must to protect the product while remaining operationally effective. Additionally, reusable packaging reduces the waste that our customers are left to dispose of as well as saves landfill space. While we have been recognized for innovative solutions to maintain temperature and prevent product spoilage, it is also gratifying to be recognized for the sustainability benefits of our approach.”
Cardinal Health will give a presentation on their award-winning entry at the RPA Reusable Packaging Learning Center at Pack Expo International in Chicago on November 8, 2016.
Emirates starts Moscow pharma service
Moscow, Russia: Emirates started on 1 October, two daily A380 services –Dubai to Guangzhou, China, and Dubai to Moscow, Russia – adding top its existing 40 Emirates destination cities.
The new dailies follow last month’s opening of a purpose-built temperature-sensitive pharmaceutical centre at Dubai World Central Airport.
Pharma logistics firms must work with regulators
Dubai, UAE: Logistics providers must work closely with regulators to avoid temperature excursions, according to the chairman of the Cool Chain Association ((CCA).
Canadian supply chain magazine MM&D reported on the Cool Chain Association’s (CCA) Pharma and Biosciences Conference 2016, held this month, where Sebastiaan Scholte said that a more unified approach was needed by pharma supply chain providers to help to combat annual losses of up to $35 billion resulting from wasted pharmaceutical product temperature excursions.
“Temperature controlled logistics is expected to grow by nine percent every year, leading to a global cool chain industry worth around $16.7 billion by 2020,” said Scholte.
“However, the patchwork of regulations around the world, as well as the huge amount of data being collected as we process pharma goods, means we have to navigate a highly complex system.”
Scholte added that industry must work closely with regulators to ensure that any new legislation does not elongate the time-critical cool chain process.
“Open dialogue between industry and regulators is vital to ensure every voice in the cool chain is heard to help us achieve a slicker, more transparent supply chain that meets the evolving needs of the pharmaceutical marketplace.”
Therese Puetz, chief executive, Karavan Management Consulting, told delegates that halal pharma was a growing and important market. The smart cool chain was the next innovation, she said.
Onset expands InTemp for pharmaceutical cold chain monitoring
Boston, MA, US: Onset is expanding it InTemp family of pharmaceutical cold chain management products with the two new solutions: InTemp CX500 Series temperature loggers and the InTempConnect cloud-based data warehousing service.
Together with Onset’s CX400 Series loggers and InTemp mobile application, they provide end-to-end visibility throughout the pharmaceutical supply chain—from the manufacturing plant, across distribution, to pharmacies, clinics and other healthcare facilities.
Bluetooth Low Energy enabled InTemp CX500 Series loggers provide in-transit temperature monitoring—without the need to open boxes—to reduce temperature excursions and handling errors. The InTempConnect cloud-based data warehousing service enables command-center control over all logger deployments throughout the global supply chain. And like all InTemp products, the new solutions achieve 21 CFR Part 11 compliance, ensuring electronic records and electronic signatures are trustworthy and reliable.
The products wewre launched at the 14th Cold Chain GDP & Temperature Management Logistics Global Forum, at the Hynes Convention Center in Boston this week (26 September 2016)
“Today’s temperature monitoring solutions have not kept pace with growing government and market pressures for pharmaceutical companies to validate the integrity of their products and gain tighter control over costs,” said Paul Della Villa, product marketing manager, Onset.
“Our expanded line of InTemp pharmaceutical cold chain monitoring solutions addresses that innovation gap by harnessing mobile and cloud technology to bring unprecedented ease of use, cost effectiveness, and comprehensive functionality to monitoring the entire distribution chain.”
Maersk and IAG Cargo eye up lucrative pharma market
London, UKJ: Maersk and IAG Cargo announced today that they are expanding their cool container capabilities in a bid to capture more perishable volumes.
Maersk Line has ordered 14,800 reefers, for replacement and expansion. It already has more than 270,000, with an average fleet age of 7.9 years.
All Maersk’s reefers can be tracked and contents monitored. equipment. Shereen Zarkani, head of reefer management, Maersk Line says iInvesting in reefers will allow Maersk to cement its position in a fast-growing market.
Reefer shipping outperformed dry cargo in the first half of 2016, providing one of the few growth markets in a generally poor year. Data collected between January and June by consultant Seabury shows reefer cargo racked up 163,000 extra teu on the same period last year. Chilled foods increased by 7% and frozen by 4%.
IAG Cargo has signed with hi-tech insulation provider Va-Q-tec for a global container rental agreement. The containers differ from Maersk’s reefers, in that they are passive with no electrical input, but provide six temperature ranges.
IAG Cargo has seen its pharmaceutical and cold chain volumes rise significantly since 2011. In 2014, volumes rose 55%, and last year it saw growth of 44%. “We are pretty pleased with that,” said Alan Dorling, IAG’s global head, pharmaceuticals and life sciences.
While the sea freight industry has increasingly made inroads into the perishables business with better technology, causing some modal shift, it has yet to eat significantly into the high-value high-yield pharmaceutical market. But Maersk is looking into it, said Hristo Petkov, pharma segment lead for the line’s reefer division.
“The reefer containers are the same regardless of category or commodity, so they are also designed to carry specific pharma products,” he told the Loadstar.
“We already ship pharmaceutical products, but we clearly see this as a potential growth category – ie conversion to ocean transportation – meaning this is still early days even when considering the steep conversion developments that are happening nowadays.
“From the pharma shippers we serve already and those inquiring, we understand their special requirements and questions that need answers for them to enter further conversion; so we plan to develop a quality service that is matching expectations – as such we are actively working to enable standardization and share best practices across the sector in handling pharma products.”
UK: New temperature testing chamber for southeast
London, UK: DBS Temperature Control Engineering is poised to open a massive new temperature testing chamber big enough to house a rigid vehicle and trailer, designed to help pharma companies comply with stringent legislation on temperature control.
David Brett, director, DBS, told GCCN that the company already has a chamber but this is only large enough to test a long wheel-base Sprinter. “The 480 cubic metre chamber is 20m long, 4m wide, and 6m high. That actually accommodates any UK vehicle, including a wagon and drag.”
The chamber can test within a large temperature range of -30 to +50°C. DBS introduces a forced ambient temperature and then monitors the load-space within the vehicle which could, for example, have a set point temperature of +20°C.
There are multiple data loggers within the load area. DBS will stabilise the temperature at whatever the pharma company requests and this is recorded. Another advantage is that the chamber can be divided into two cells and have different temperatures in each cell. One customer might want -10 and the other +30°C, and the testing can take place at the same time.
“It’s quite often a two-stage service because we’re providing the chamber in addition to the data logging equipment that we’re using which is capable of producing temperature mapping reports that are externally validated to meet Installation Qualification and Operational Qualification requirements. ”The new chamber will mean that temperature testing can now take place for the first time in the South of England – up until now pharmaceutical companies have been forced to take their vehicles to either north Staffordshire or the Cambridge area.
“There is huge demand for this – when you think about the cost of moving vehicles around, for example taking one from Heathrow to North Staffordshire means that you lose that vehicle for the day.”
The new chamber went into operation in April and DBS will build a second, similar chamber later this year to cope with the current influx of orders. Demand for accurate and consistent temperature control follows the introduction of tough legislation in the form of Good Distribution Practice which came into force in 2012. This requires that pharmaceutical products and medicines are obtained from the licensed supply chain and are consistently stored, transported and distributed under appropriate and compliant conditions.
Other future plans for DBS include introducing a new laboratory to calibrate temperature testing equipment in-house to ISO 17025 standards.
Brett set up DBS in 2010 after many years’ experience in the cold chain industry. The company also specialises in insulated containers along with real-time temperature tracking.